New York, NY -- (ReleaseWire) -- 04/16/2013 --Pfizer Inc. (NYSE: PFE) recently announced that its investigational compound palbociclib (PD-0332991), an oral and selective inhibitor of cyclin dependent kinases (CDK) 4 and 6, has received Breakthrough Therapy designation by the United States Food and Drug Administration (FDA) for the potential treatment of patients with breast cancer.
Enacted as part of the 2012 FDA Safety and Innovation Act (FDASIA), Breakthrough Therapy designation is intended to expedite the development and review of a potential new medicine if it is “intended, alone or in combination with one or more other drugs, to treat a serious or life-threatening disease or condition and preliminary clinical evidence indicates that the drug may demonstrate substantial improvement over existing therapies on one or more clinically significant endpoints.”
The Breakthrough Therapy designation is distinct from the FDA’s other mechanisms to expedite drug development and review.
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Taleris, a joint venture between GE Aviation, subsidiary of General Electric Company (NYSE: GE), and Accenture, announced the opening of its headquarters facility in Irving, Texas. The Honorable Beth Van Duyne, Mayor of Irving and Taleris President Norm Baker officially opened the facility along with City of Irving officials and Taleris directors from parent companies GE Aviation and Accenture.
“Taleris will use intelligent operations technology and services to help commercial operators manage their maintenance, planning, recovery and flight operations more efficiently,” stated Baker.
“Unscheduled maintenance, delays and cancellations cost airlines billions of dollars each year. Our intelligent operations services use proprietary algorithms to monitor data collected from aircraft equipment to diagnose and predict aircraft maintenance issues before they occur. We also take into account recovery and planning for our customers’ overall flight operations.”
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